Science and Technology cooperation Exploration: Global Science and Technology Project (Phase 2)In the rapidly developing field of science and technology, innovative projects are constantly emerging. In recent years, there have been significant opportunities in all aspects surrounding cutting-edge technology. International cooperation in science and technology is of great significance in jointly solving global problems, accelerating scientific and technological progress, promoting economic development, promoting personnel training and exchanges, and building a scientific and technological community. The PAI community is committed to building a bridge of scientific and technological exchange, solving common challenges, promoting international cooperation and development, and promoting world peace and prosperity.
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01 / A technique for using bacterial peptides to prevent dental diseases Project summary: The University of Toronto, located in Toronto, Ontario, Canada, is a public federal research university. The University of Toronto is made up of 11 faculties and is a Canadian and world leader in a number of fields. The number of scientific research papers published by the University of Toronto every year in North America is second only to Harvard University, the number of citations ranks in the top five in the world, and is one of only two members of the Association of American Universities outside the United States. Dental diseases are often caused by an imbalance in the balance of the oral microbiome. In daily life, the number of bacteria that are beneficial to health may decrease, increasing the number of more virulent strains in the mouth, leading to an increased probability of oral disease. By using symbiotic bacteria to target and reduce these pathogens, this harmful change can be reversed. Streptococcus salivarius is an organism that secretes modified peptide antibiotics (i.e., lactate antibiotics) that target a variety of different pathogen species, eliminating bad breath and strep throat and reducing dental caries. Studies have shown that the novel lactate antibiotic of Streptococcus salivarius SALI-10 induces an anti-inflammatory response in neutrophils and macrophages in a symbiotic manner and induces bacteriophagy. Researchers at the University of Toronto have isolated a strain of Streptococcus salivarius that can secrete a range of lactate antibiotics that interfere with the growth of periodontal pathogens, including Bacteroides gingivalis and Bacteroides rhizodontidis, as well as multidrug-resistant (MDR) pathogens such as Streptococcus pneumoniae and Enterococcus faecalis, without affecting the core symbiotic microbial community in the mouth. The research group has isolated a strain of S. salivarius containing three lactate antibiotics from 78 strains from healthy adults, sequenced its genome, and isolated and structurally characterized the peptides using high-resolution mass spectrometry and two-dimensional nuclear magnetic resonance. The antibiotic potential of SALI-10 has been tested against 24 different pathogenic bacterial species21 and a variety of biofilms, while its immunomodulatory potential has been tested using neutrophils and monocytes. The project has been patented and large-scale production has been achieved, and the foreign side hopes to cooperate in the form of cooperative production and investment.
02 / BiobiN® - Waste disposal system Project summary: BiobiN Technologies Australia is a high-tech company that has achieved successful commercial operations in South Australia, the United Arab Emirates and Singapore and holds a complete set of patents for ecological treatment systems for organic waste such as food waste and agricultural waste. BiobiN® is a field capture and containment system for organic material handling. BiobiN® aeration systems reduce bacteria and other pathogens when starting the composting process of organic materials. The composting process also maximizes the amount of organic material that can be collected, which can be treated or partially treated to be added to soil conditioners, compost and other products. The project has been patented and large-scale production has been achieved, and the foreign side hopes to cooperate in the form of cooperative production and investment.
03 / International Atomic Energy Agency (IAEA) 'Light of Hope' Initiative to establish 'Anchor Centre' Project summary: In February 2022, the International Atomic Energy Agency (IAEA) launched the "Ray of Hope" cancer diagnosis and treatment Initiative, supporting the establishment of the "anchor center" in the "Ray of Hope" region, providing radiation treatment equipment to member states, conducting education and training to strengthen research and innovation. To help member states comprehensively improve radiological diagnosis and cancer treatment capacity. Through the establishment of "anchor centers", the IAEA helps recipient countries to strengthen education and training, enhance research capacity, improve the overall radiation therapy and medical imaging infrastructure, and improve the level of cancer treatment in their countries and regions. On the other hand, based on the center, training and research activities are carried out in the region, receiving scientific visits, expert exchanges and participating in international atomic energy coordination research projects. To apply to become an Anchor Center, you must meet the following criteria: have a long history of 19 radiotherapy and nuclear medicine training activities in the region; Having the expertise, human resources, a sound quality management system and adequate infrastructure (teaching premises, research infrastructure, equipment and other related facilities) needed to provide training services; A well-developed quality assurance program in line with institutional standards; Having sufficient personnel and organizations dedicated to training activities; Experience and management capacity in providing training services at national and regional levels, in particular in hosting refresher courses and organizing training events; Establish good working relationships with other relevant domestic agencies; Carry out international knowledge exchange and networking activities, and demonstrate research innovation ability and results by issuing publications, organizing conferences, participating in or leading clinical research projects, etc. It is understood that 14 units are interested in becoming "anchor centers" and have submitted applications to the International Atomic Energy Agency. It is reported that becoming an "anchor center" requires the following procedures: (1) The Member States, through their permanent missions, submit letters of application to the Director General of the International Atomic Energy Agency; (b) meet with the relevant IAEA authorities to conduct in-depth discussions on the candidacy; (c) to submit a formal application and supporting documents to the International Atomic Energy Agency; (4) The internal committee of the institution will review the application materials and make comments and suggestions; (5) Bilateral talks on International Atomic Energy support for the Anchor Centre; (6) Signing of two agreements (an agreement on collaborating or anchoring centres, and a separate agreement determining the support provided by IAEA).
04 / DUS test technology for vegetable varieties Project summary: Naktuinbouw, the Dutch horticultural crop Inspection Agency, was formed in 2000 by the merger of the Dutch Arboricultural Crop Inspection Agency (NAKB), the Dutch Flower Crop Inspection Agency (NAKS) and the Dutch Vegetable and Flower Seed Inspection Agency (NAKG). Mainly responsible for DUS testing of plant varieties, VCU testing of crop and vegetable varieties, seed quality inspection, seed health quarantine inspection, variety authorization and registration. The unit is one of 22 EU-certified testing centres, believed to test 1,070 crops, and has 15 hectares of experimental land at the headquarters, Lisse and Tollebeek, with a fifth of the land fallow each year. Its total number of about 250 people, of which 88 people in the variety testing department. About 2,700 varieties are tested every year, of which the number of varieties registered domestically, protected domestically and protected by the EU is basically the same, involving 400 crop varieties, 1,400 vegetables and 900 flowers. In recent years, it has taken the lead in undertaking the EU Horizon project of "Unification and Validation of SNP Markers for International Tomato Variety Management" and the UPOV project of "Unification of Resistance identification methods for Vegetable varieties". This project, in cooperation with the Netherlands Horticultural Crop Inspection Bureau and the Institute of Vegetable and Flower Research of the Chinese Academy of Agricultural Sciences, takes vegetable varieties (including five species or genera including tomato, cucumber and cabbage) as research objects. Through joint research, technical exchange, information sharing and standard setting, Innovative and unified methods and technologies of DUS testing, molecular identification, quality and resistance detection, image analysis, statistical analysis and other related crops, to build and improve the data, images and molecular fingerprint database of known vegetable varieties in China. The project has been patented, and the foreign party hopes to carry out cooperation in the form of cooperative research and development.
05 / Agroecological water-saving plant box Project summary: Dutch technology company Groasis focuses on developing unique technologies and products for tree planting and water saving. The company helps improve woodlands and ecosystems around the world through innovative ways to conserve water, and plays an important role in drought and water scarcity. The product won the 2010 Popular Science Green Technology Best Innovation of the Year award and is widely used in various projects such as tree planting, agriculture and ecological restoration. The company was designated a "national icon" by the Dutch government in 2016. Over the past 20 years, Groasis' technology has successfully planted more than 20 million trees and plants in 55 countries. The company's main product is the Waterboxx tree box, which acts as a plant incubator, protecting newly planted saplings and the ground around them from the sun's heat while providing water for the plants. The lid of the product collects rainwater and water that condenses during the night and then stores it in a bucket; The water-filled reservoir releases a small amount of water (about 50 ml per day) into the ground through a wick to water the trees and promote the development of the tree root structure. The temperature and humidity inside the box are more stable day and night than outside the box. The goal is to use less than 90% water, grow at 90% lower cost, and have a 90% survival rate. The introduction of this patented technology and the pilot application and promotion of related products in the northwest region of China can effectively restore nature, reduce dust storms and erosion, sustainably regenerate degraded land, increase biodiversity on degraded land, and help diversify the economy by creating jobs in related industries. The project has been patented, has achieved large-scale production, the foreign party hopes to carry out cooperation in the form of patent license trade and cooperative research and development.
06 / Sweat Analysis Smart Patch Project summary: The Barcelona Institute of Microelectronics (IMB-CNM), part of the Spanish Higher Research Council (CSIC), is the largest research institute in Spain dedicated to the development of micro and nanotechnologies (MNT) and Microsystems, mainly engaged in basic and applied research and development, education and training in micro and nanotechnologies, components and systems. Providing technical solutions to societal challenges. The smart patch makes contact with sweat and triggers the chemical reaction of the electrode, and by analyzing the sweat composition information, it can understand the dehydration of the athlete and develop a personalized hydration plan, and users can obtain hydration guidelines through the app. In clinical trials at the Sant Joan de Deu Hospital in Barcelona, the technology was also found to be useful in screening patients with cystic fibrosis. The product is now in the prototyping stage of a final patch and mobile app, with plans to go on sale early next year. Currently, the project has signed a licensing agreement with Catalan Sweanty to exploit and develop commercial products. The project has been patented and has achieved small-scale trial production, and the foreign party hopes to carry out cooperation in the form of technology transfer and patent license trade.
07 / Crop water evaporation measuring instrument Project summary: The Institute for Sustainable Agriculture (IAS), part of the Spanish Higher Research Council (CSIC), is located at the experimental farm Alameda del Obispo in Cordoba del Guadalquivel, and conducts research on agronomic, plant genetic improvement and crop protection to address drought and soil conservation issues. We will promote the development of agricultural food science and technology. The Institute has technologies in hydrology irrigation, plant genetic improvement, crop modelling, remote sensing applications, soil erosion and conservation. The Crop Water Evaporation Meter (Cordova-ET) measures crop temperature and wirelessly transmits data in real time using Internet of Things (IoT) technology to accurately calculate evapotranspiration and improve irrigation water efficiency. The device uses sensors that are being used on the market, is simple to operate, requires no experience, is easy to use by farmers, researchers and professionals, and costs significantly less than current similar devices. The device can also measure local weather conditions and be used for the protection of historic sites. The tool, funded by the Food and Agriculture Organization of the United Nations (FAO) and the Swedish Development Assistance Agency, is currently deployed in eight countries in North Africa and the Middle East. Its research group has opened source shared software so that anyone can access and use the technology. The results are in the journal Frontiers in Agronomy. The project has achieved mass production, and the foreign side hopes to cooperate in the form of export products and open source shared software. |
